The Science

While our motivation is simple, the science that goes into creating a lung surfactant that resembles the real thing is a little more complicated.

Mirrors native lung surfactant.

Infasurf® (calfactant) resembles native calf lung surfactant in both composition and activity due to our lung lavage manufacturing process.

41% Disaturated Phosphatidylcholine (DSPC)

10% Phosphatidyl Glycerol (PG)

5% Cholesterol (Chol)

4% Other Phospholipids (PLS)

9% SP-A

2% SP-B, SP-C

29% Unsaturated Phosphatidylcholine (USPC)

  • All essential components of native calf lung surfactant are maintained in Infasurf® (calfactant) due to our unique lavage manufacturing process2
  • Surfactant protein B (SP-B) is essential for forming the surfactant film that lines the alveoli3,4
  • Infasurf® (calfactant) is the only surfactant that retains natural cholesterol, which aids the rapid spread of the surfactant film during respiration5